Advances in Mental Health, Vol 11, No 3 (2013)

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Using QEEG parameters (asymmetry, coherence, and P3a Novelty response) to track improvement in depression

Leon Petchkovsky, Kirstin Robertson-Gillam, Juri Kropotov, Michael Petchkovsky

Abstract


This pilot study reports the findings from a sub-group of 9 patients, from a cohort of 32 middle-aged ambulant depressive patients undergoing an intensive 8 week choral singing programme, who received “before” and “after” QEEGs (resting state and the WinEEG VCPT ERP protocol). “Before” and “after” mental state examinations and Beck Depressive Inventory showed significant improvement  (p< 0.001). Group spectral analysis of resting QEEG showed greater L/R hemispheric symmetry of activity, reduction of right polar pre-frontal hyper activity, and reduction of hypercoherence (all reported depressive parameters).

ERP results revealed that an initially  heightened P3a Novelty Cingulate Gyrus response reduced significantly over the course of treatment (p






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